3 things to know about Saxenda, the new powerful weight loss drug approved by FDA.
New class of weight loss drug
Saxenda(liraglutide) is a new class of medications also called incretins or glucagon-like peptide-1 (GLP-1) receptor agonist. Approved previously for patients with diabetes at a lower dose as Victoza. Containing the same active ingredient (liraglutide) at different doses (3 mg and 1.8 mg, in Victoza and Saxenda, respectively), Saxenda is approved solely for weight loss while Victoza is approved solely for diabetes.(Do not ask me why – that is how FDA works, unless data is presented, the same medicine may have different indications at different doses).
Healthy weight loss
How effective is Saxenda for weight loss?
According to the statement from the FDA, the safety and effectiveness of Saxenda were evaluated in three clinical trials that included approximately 4,800 obese and overweight patients with and without significant weight-related conditions. All patients received counseling regarding lifestyle modifications that consisted of a reduced-calorie diet and regular physical activity.
Non-diabetic patients losing weight on Saxenda
Results from a clinical trial that enrolled patients without diabetes showed that patients had an average weight loss of 4.5 percent from baseline compared to treatment with a placebo (inactive pill) at one year. In this trial, 62 percent of patients treated with Saxenda lost at least 5 percent of their body weight compared with 34 percent of patients treated with placebo.
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Diabetes patients losing weight on Saxenda
Results from another clinical trial that enrolled patients with type 2 diabetes showed that patients had an average weight loss of 3.7 percent from baseline compared to treatment with placebo at one year. In this trial, 49 percent of patients treated with Saxenda lost at least 5 percent of their body weight compared with 16 percent of patients treated with placebo.
Patients using Saxenda should be evaluated after 16 weeks to determine if the treatment is working. If a patient has not lost at least 4 percent of baseline body weight, Saxenda should be discontinued, as it is unlikely that the patient will achieve and sustain clinically meaningful weight loss with continued treatment.
The good news is that Saxenda is a bit more powerful in helping patients lose weight, and it targets insulin resistance, the root cause of weight in most people!
Compared to the other new weight loss medication, Contrave, Saxenda has better weight loss results although the price of Saxenda and the fact that it is a subcutaneous injection might present a barrier for its use!
Locations for physicians offering Saxenda in New York, New Jersey and Pennsylvania
Weight loss centers that accept insurance
King Of Prussia Weight Loss & Sleep Center: 987 Old Eagle School Rd, Ste 712, Wayne, PA, 19087 Ph: 215-676-2334
NYC Insurance Weight Loss & Sleep Center: 2003, Bath Avenue, Brooklyn, NY, 11214 Ph: 1-718-946-5500.
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